The standalone autoloader is dedicated to just one thing, duplication. An autoloader that is connected to a PC is just one of the functions the computer offers. Not only does this tie up your PC, limiting your ability to perform other functions, but will be more complicated to operate. The Standalone autoloader can be operated by simple 1 button operations instead of requiring complicated software to install. Again, when you're connected to a PC, any time the computer freezes or has a glitch, the duplicator will generate an error and limit your production and quality capabilities.